#160456

Anti-FN-EDB [2DS.1]

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Cat. #160456

Anti-FN-EDB [2DS.1]

Cat. #: 160456

Sub-type: Primary antibody

Unit size: 100 ug

Target: Extra domain B of fibronectin, EDB-FN

Class: Monoclonal

Application: ELISA ; IHC

Reactivity: Human

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Tambet Teesalu

Institute: University of Tartu

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-FN-EDB [2DS.1]
  • Research fields: Cancer;Cell biology
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Application: ELISA ; IHC
  • Description: Oncofetal fibronectin (FN-EDB) and tenascin-C C domain (TNC-C) are nearly absent in extracellular matrix of normal adult tissues but upregulated in malignant tissues. Both FN-EDB and TNC-C are developed as targets of antibody-based therapies.This series of antibodies has been validated in vitro against glioblastoma (GBM) and prostate carcinoma xenografts, and to non-malignant angiogenic neovessels induced by VEGF-overexpression. Please see our related anti-FN-EDB antibodies from University of Tartu.

Target Details

  • Target: Extra domain B of fibronectin, EDB-FN
  • Target background: Oncofetal fibronectin (FN-EDB) and tenascin-C C domain (TNC-C) are nearly absent in extracellular matrix of normal adult tissues but upregulated in malignant tissues. Both FN-EDB and TNC-C are developed as targets of antibody-based therapies. This series of antibodies has been validated in vitro against glioblastoma (GBM) and prostate carcinoma xenografts, and to non-malignant angiogenic neovessels induced by VEGF-overexpression. Please see our related anti-FN-EDB antibodies from Universit...

Applications

  • Application: ELISA ; IHC

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Lingasamy et al. 2019. Biomaterials. 219:119373. PMID: 31374479.