Cat. #151153
Anti-Epithelia [PR 4D1]
Cat. #: 151153
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Epithelia (colonic)
Class: Monoclonal
Application: IHC
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Walter Bodmer
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Epithelia [PR 4D1]
- Research fields: Cell biology;Cell signaling and signal transduction
- Clone: PR 4D1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 140 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Description: PR 4D1 may be useful for histological diagnosis of colon disorders. Wide reactivity with GI tract. Reacts with a high MW glycoprotein in human colonic mucus, epithelial cells and cell membranes.
- Immunogen: Mucosal scrapings and membrane preparations from normal colorectal epithelium and possibly booster inoculations with the colon carcinoma cell line HT29.
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Epithelia (colonic)
- Molecular weight: 140 kDa
- Target background: PR 2D3 reacts with a cell membrane component of cells in the pericrypt sheath; with smooth muscle cells and myofibroblasts. This antibody is considered to be the gold standard for the identification of myofibroblasts.
Applications
- Application: IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Richman et al. 1987. Int J Cancer. 39(3):317-28. PMID: 2434440.
- Monoclonal antibodies to human colorectal epithelium: markers for differentiation and tumour characterization.
