#151308

Anti-EB1 [EB1-CL 1A11/4]

Cat. #151308

Anti-EB1 [EB1-CL 1A11/4]

Cat. #: 151308

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: EB1

Class: Monoclonal

Application: ELISA ; IF ; IHC ; IP ; WB

Reactivity: Human ; Primate ; Dog

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: University of Leeds

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-EB1 [EB1-CL 1A11/4]
  • Research fields: Cancer;Cell biology;Cell signaling and signal transduction
  • Clone: EB1-CL 1A11/4
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: CD1
  • Reactivity: Human ; Primate ; Dog
  • Host: Mouse
  • Application: ELISA ; IF ; IHC ; IP ; WB
  • Description: EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex.
  • Immunogen: EB1 deltaC1 mutant
  • Isotype: IgG2b
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: HeLa cells

Target Details

  • Target: EB1
  • Tissue cell line specificity: HeLa cells
  • Target background: EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex.

Applications

  • Application: ELISA ; IF ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Bowen et al. 2011. J Cell Biol. 194(2):187-97. PMID: 21788367.
  • Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia.
  • Askham et al. 2002. Mol Biol Cell. 13(10):3627-45. PMID: 12388762.
  • Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.