EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex.
| Institute |
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| University of Leeds |
| Cat. #: | 151308 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction |
| Application: | ELISA ; IF ; IHC ; IP ; WB |
| Target: | EB1 |
| Reactivity: | Human ; Primate ; Dog |
| Clone: | EB1-CL 1A11/4 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Immunogen: | EB1 deltaC1 mutant |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Bowen et al. 2011. J Cell Biol. 194(2):187-97. PMID: 21788367. Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia. Askham et al. 2002. Mol Biol Cell. 13(10):3627-45. PMID: 12388762. Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome. |
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