Cat. #151234
Anti-Cytochrome P450 4A1, 2C11 [Clo1]
Cat. #: 151234
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Cytochromes P450 4A1, 2C11. CYP4A1, CYP2C11
Class: Monoclonal
Application: ELISA ; WB
Reactivity: Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Roland Wolf
Institute: University of Dundee
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytochrome P450 4A1, 2C11 [Clo1]
- Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
- Clone: Clo1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 51/51.5 kDa
- Reactivity: Rat
- Host: Mouse
- Application: ELISA ; WB
- Description: The CYP2 family are part of the microsomal drug metabolising system that is responsible for oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. The hepatic CYP4A enzymes are important fatty acid and prostaglandin omega-hydroxylases that are highly inducible by fibric acid hypolipidemic agents and other peroxisome proliferators. In humans, 4A1, 4A2, & 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels.
- Immunogen: Rat liver cytochrome P450 2C11 and 4A1
- Isotype: IgG2b
Target Details
- Target: Cytochromes P450 4A1, 2C11. CYP4A1, CYP2C11
- Molecular weight: 51/51.5 kDa
- Target background: The CYP2 family are part of the microsomal drug metabolising system that is responsible for oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. The hepatic CYP4A enzymes are important fatty acid and prostaglandin omega-hydroxylases that are highly inducible by fibric acid hypolipidemic agents and other peroxisome proliferators. In humans, 4A1, 4A2, & 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels.
Applications
- Application: ELISA ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- "Monoclonal Antibodies Diagnostics for Individual Members of the Cytochromes P450IV Gene Family", Abstract 1.36 at the 12th Eur. Work. on Drug Metabolism, Basel, Switzerland, Sept. 16-21, 1990.
- "Monoclonal Antibodies Diagnostics for Individual Members of the Cytochromes P450IV Gene Family", Abstract 205 at the VIIIth Inter. Symp. on Microsomes and Drug Oxidations, Stockholm, Sweden, June 25-26, 1990.
- Tzeng et al. 2012. Evid Based Complement Alternat Med. 2012:827278. PMID: 22253647.
- Vinegar-Baked Radix Bupleuri Regulates Lipid Disorders via a Pathway Dependent on Peroxisome-Proliferator-Activated Receptor-a in High-Fat-Diet-Induced Obese Rats.
