Cat. #152697
Anti-cMyc [PM3E7]
Cat. #: 152697
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: cMyc, c-Myc
Class: Monoclonal
Application: IHC ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Gerard Evan
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-cMyc [PM3E7]
- Cancer: Breast cancer;Gynaecologic cancer;Lung cancer
- Cancers detailed: Breast cancer;Broadly Applicable;Cervix;Colorectal;Lung;Stomach
- Research fields: Cancer;Cell biology;Genetics;Stem cell biology
- Clone: PM3E7
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IP ; WB
- Description: The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients.
- Immunogen: A synthetic peptide APSEDIWKKFEL corresponding to amino acids 44-55 of c-Myc coupled to PPD
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: cMyc, c-Myc
- Target background: The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients.
Applications
- Application: IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Evan et al. 1988. Curr Top Microbiol Immunol. 141:189-201. PMID: 3063442.
- Immunological probes in the analysis of myc protein expression.
