Cat. #151185
Anti-Cdk1 [Y100.4]
Cat. #: 151185
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Cyclin Dependent Kinase 1 (Cdk1, Cdc2)
Class: Monoclonal
Application: WB ; WB
Reactivity: Schizosaccharomyces pombe
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Julian Gannon
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cdk1 [Y100.4]
- Alternate name: Cyclin-Dependent Kinase 1; Cell Division Cycle 2, G1 To S And G2 To M; Cell Division Control Protein 2 Homolog; Cell Division Protein Kinase 1; P34 Protein Kinase; P34CDC2; CDC28A; CDC2; Cell Cycle Controller CDC2; CDKN1
- Research fields: Cancer;Cell biology;Neurobiology
- Clone: Y100.4
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Schizosaccharomyces pombe
- Host: Mouse
- Application: WB ; WB
- Description: Cdk1 (Cdc2) is a serine/threonine kinase which forms complexes with cyclins A and B which then phosphorylate a variety of target substrates to enable cell cycle progression. Therefore, Cdk1 is a marker for proliferating tumour cells.
- Immunogen: Peptide spanning the C-terminal 14 residues of S. pombe Cdk1.
- Isotype: IgG2b
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Cyclin Dependent Kinase 1 (Cdk1, Cdc2)
- Target background: Cdk1 (Cdc2) is a serine/threonine kinase which forms complexes with cyclins A and B which then phosphorylate a variety of target substrates to enable cell cycle progression. Therefore, Cdk1 is a marker for proliferating tumour cells.
Applications
- Application: WB ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Mennie et al. 2018. Nat Commun. 9(1):586. PMID: 29422503.
- Chang et al. 2013. PLoS Genet. 9(11):e1003936. PMID: 24244195.
- Fission yeast shelterin regulates DNA polymerases and Rad3(ATR) kinase to limit telomere extension.
- Radcliffe et al. 1998. Mol Biol Cell. 9(7):1757-71. PMID: 9658169.
- Identification of novel temperature-sensitive lethal alleles in essential beta-tubulin and nonessential alpha 2-tubulin genes as fission yeast polarity mutants.
- Yamano et al. 1996. EMBO J. 15(19):5268-79. PMID: 8895572.
- The role of proteolysis in cell cycle progression in Schizosaccharomyces pombe.
