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#154794

Anti-CD8 [SPVT8]

Cat. #154794

Anti-CD8 [SPVT8]

Cat. #: 154794

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: CD8

Class: Monoclonal

Application: FACS ; IP

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Netherlands Cancer Institute

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-CD8 [SPVT8]
  • Alternate name: Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen
  • Research fields: Cell biology;Immunology
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 32 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IP
  • Description: CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides
  • Immunogen: Human cytotoxic T-lymphocytes
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: CD8
  • Molecular weight: 32 kDa
  • Target background: CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides

Applications

  • Application: FACS ; IP

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

References

  • de Vries et al. 1984. J Immunol. 132(1):510-9. PMID: 6197458.
  • Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.

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