Anti-CD72 [BU40] mAb

CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.

Contributors

Inventor Institute
Margaret Goodall ; D.L. Hardie ; Roy Jefferis ; Ian MacLennen University of Birmingham
Cat. #: 151433
Unit size: 100 ug
Research Fields: Immunology;Stem cell biology
Application: FACS ; IHC; IP ; WB
Target: CD72
Reactivity: Human
Clone: BU40
Host: Mouse
Class: Monoclonal
Alternate name: CD72 Molecule; CD72 Antigen; Lyb-2; CD72b; LYB2
Product description: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.
Conjugation: Unconjugated
Isotype: IgG2a kappa
Immunogen: HF B1 plasmacytoid cell line. Considered to be “late B like”.
Target background: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: RPMI 1640 + 10% FCS
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Ishida I. et al. 2003. International Immunology. 15(8):1027-34. PMID: 12882840 Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. ISBN-13: 978-0192618672 Schwarting R. et al. 1992. Am.J. of Hematol. 41(3):151-8. PMID: 1384316 Van De Velde H. et al. 1991. Nature 351(6328):662-5. PMID: 1711157

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