Anti-CD44 [BU93]

CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.

Contributors

Inventor Institute
Margaret Goodall University of Birmingham
Cat. #: 153233
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Cell biology;Cell signaling and signal transduction;Immunology
Application: IHC
Target: CD44
Reactivity: Human
Clone: BU93
Host: Mouse
Class: Monoclonal
Alternate name: Cell differentiation 44; Homing cell adhesion molecule; HCAM; phagocytic glycoprotein-1; Pgp-1; Hermes antigen; lymphocyte homing receptor; ECM-III; HUTCH-1.
Product description: The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.
Conjugation: Unconjugated
Isotype: IgG1
Target background: The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.

Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.

Leucocyte Typing VII, (2002): edited by D.Y. Mason, OUP, Oxford.

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