#152538

Anti-ADAM9 [9MO]

Cat. #152538

Anti-ADAM9 [9MO]

Cat. #: 152538

Sub-type: Primary antibody

Unit size: 100 ug

Target: ADAM9

Class: Polyclonal

Application: WB

Reactivity: Mouse

Host: Rabbit

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Carl Blobel

Institute: Hospital for Special Surgery

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-ADAM9 [9MO]
  • Research fields: Cancer;Cell signaling and signal transduction
  • Clone: 9MO
  • Tool sub type: Primary antibody
  • Class: Polyclonal
  • Conjugation: Unconjugated
  • Molecular weight: ~84 kDa (mature form), 115 kDa (pro-form)
  • Reactivity: Mouse
  • Host: Rabbit
  • Application: WB
  • Description: ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
  • Immunogen: GST-cyto corresponding to the cytoplasmic domain of murine ADAM9

Target Details

  • Target: ADAM9
  • Molecular weight: ~84 kDa (mature form), 115 kDa (pro-form)
  • Target background: ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

Applications

  • Application: WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: Whole serum
  • Storage conditions: -20° C
  • Shipping conditions: Shipping at 4° C

References

  • Guaiquil et al. 2009. Mol Cell Biol. 29(10):2694-703. PMID: 19273593.
  • Peduto et al. 2005. Cancer Res. 65(20):9312-9. PMID: 16230393.
  • Roghani et al. 1999. J Biol Chem. 274(6):3531-40. PMID: 9920899.
  • ADAM9 is involved in pathological retinal neovascularization.
  • Critical function for ADAM9 in mouse prostate cancer.
  • Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity.
  • Weskamp et al. 1996. J Cell Biol. 132(4):717-26. PMID: 8647900.
  • MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.