Adapted from Larsen et al. 2015. PLoS One. 10(2)

T47D/TR-1 Cell Line Product

The T47D/TR-1 Cell line is a breast cancer cell line resistant to tamoxifen. This cell line allows the study of the mechanisms involved in tamoxifen resistant breast cancer cell growth.

Adapted Larsen et al. 2015. PLoS One. 10(2)

T47D/S5 Cell Line Product

The T47D/S5 Cell line is the control for the fulvestrant resistant T47D/182R-1 and T47D/182R-2 cell lines.

Adapted from Larsen et al. 2015. PLoS One. 10(2)

T47D/S2 Cell Line Product

This is the control cell line for the tamoxifen resistant T47D/TR-1 and T47D/TR-2.

Adapted Larsen et al. 2015. PLoS One. 10(2)

T47D/TR-2 Cell Line Product

The T47D/TR-2 Cell line is a breast cancer cell line resistant to tamoxifen.

T47D-STn Cell Line Product

The tumour cell line, T47D-STn, was created as a breast cancer model which expresses the Sialyl-Tn, STn, antigen.

T47D-E2J Cell Line Product

The parental T47D cell line was established from the pleural effusion of a ductal carcinoma of the breast. The tumour cell line, T47D-E2J, was created as a breast cancer model […]

Adapted from Larsen et al. 2015. PLoS One. 10(2)

T47D-182R-1 Cell Line Product

The T47D-182R-1 cell line is an adherent breast cancer cell line resistant to fulvestrant (Faslodex). It is derived from the human breast cancer cell line – T47D/S5 by long term […]

Representative pictures of parental (T47D/S2 and T47D/S5); tamoxifen (TR-1 and TR-1) and fulvestrant (182R-1 and 182R-2) resistant cell lines treated for five days with dasatinib (1 ?M) or DMSO (control). Published in Larsen et al. 2015. PLoS One. 10(2)

T47D-182R2 Cell Line Product

The T47D-182R2 Cell Line is a breast cancer cell line resistant to fulvestrant. Treatment with the steroidal antiestrogen fulvestrant has proven effective upon progression on tamoxifen therapy and is now […]

Breast cancer Page

[…] new pathways and develop improved in vitro models of breast cancer.  Anti-oestrogen resistant MCF7 and T47D cell lines  These have been derived from human breast cancer cell lines, MCF7 and […]