Human uveal melanoma M619 cell line

This cell line was derived from primary choroidal melanomas. This cell line is positive for type VI collagen via IHC.

Contributors

Inventor Institute
Karla Daniels The University of Iowa
Cat. #: 160514
Tool sub type: Primary
Unit size: 1×10^6 cells / vial
Research Fields: Cancer;Drug development
Organism: Human
Tissue: Eye
Model: Cancer Model
Cancer Types In Detail: Uveal melanoma
Product description: Uveal melanoma is a rare, but deadly, cancer of of the eye involving the uvea (iris, ciliary body, or choroid). Tumors arise from melanocytes mostly in the uvea, but can also arise from the conjunctiva and other sites within the eye. This cell line was derived from primary choroidal melanomas. This cell line is positive for type VI collagen via IHC.
Conditional: No
Cellosaurus ID: CVCL_8472
Parental cell line: Derived from primary human uveal melanoma
disease: Cancer
Format: Frozen
Shipping conditions: Dry ice
Growth medium: RPMI 1640 with 1% insulin-selenium-transferrin, 10mM HEPES, supplemented with 5% heat-inactive FBS, 60 IU/mL Penicillin and 100 IU/mL Streptomycin, and 100mg/L L-Glutamate.
References:

Folberg et al. 2008. Invest Ophthalmol Vis Sci. 49(11):4697-701. PMID: 18689700.

Folberg et al. 2007. Invest Ophthalmol Vis Sci. 48(7):2967-74. PMID: 17591861.

Daniels et al. 1996. Lab Invest. 75(1):55-66. PMID: 8683940.

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