Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologues recombination DNA repair pathway. Rad51 forms a nucleoprotein filament through binding Rad52 and single stranded DNA that are exposed following double strand breaks. This filament initiates recombination. Rad 51B, Rad51C, Rad51D, XRCC2 and XRCC3 (X-Ray Repair Cross Complementing […]
| Inventor | Institute |
|---|---|
| Stephen West | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151326 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | IP ; WB |
| Target: | Rad51 |
| Reactivity: | Human |
| Clone: | SWE26 |
| Host: | Rabbit |
| Class: | Polyclonal |
| Product description: | Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologues recombination DNA repair pathway. Rad51 forms a nucleoprotein filament through binding Rad52 and single stranded DNA that are exposed following double strand breaks. This filament initiates recombination. Rad 51B, Rad51C, Rad51D, XRCC2 and XRCC3 (X-Ray Repair Cross Complementing 2 and 3) are Rad51 paralogs and are also components of the homologous recombination pathway. |
|---|---|
| Conjugation: | Unconjugated |
| Immunogen: | Human Rad51 N-Terminal region Peptide C. (VEEESFGPQPISRLE) linked to KLH |
| Target background: | Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologues recombination DNA repair pathway. Rad51 forms a nucleoprotein filament through binding Rad52 and single stranded DNA that are exposed following double strand breaks. This filament initiates recombination. Rad 51B, Rad51C, Rad51D, XRCC2 and XRCC3 (X-Ray Repair Cross Complementing 2 and 3) are Rad51 paralogs and are also components of the homologous recombination pathway. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | Whole serum |
| Storage conditions: | '-15° C to -25° C |
| Shipping conditions: | Dry ice |
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