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Patient Derived Xenografts (PDX) available now!
We have expanded our research tool offerings to include Patient–Derived Xenograft (PDX) models.
CancerTools.org now provide a large, diverse collection of:
- Breast cancer PDX models, deposited by Professor Alana Welm, from the University of Utah. This includes models of the most advanced and lethal forms of breast cancer, such as aggressive, metastatic and treatment-resistant subtypes.
Read about our breast cancer PDX models
What are PDX models?
PDX models are generated by engrafting tumour tissues from patients into immunodeficient mice.
Image: Schematic illustrating the establishment of PDX models by grafting tumour tissues from a patient into immunodeficient mice, created with Biorender.
What are the key benefits of using PDX models?
- Highly valuable in recapitulating of patient tumour characteristics, including intratumour heterogeneity, genomic features, metastatic patterns, and drug responses.
- Highly translatable preclinical models that can be used to more accurately test therapy efficacy and predict patient drug responses than traditional models.
- Superior choice for studying advanced cancers than traditional models that fail to accurately recapitulate metastasis.
Explore our collection of breast cancer or register interest for the upcoming NSCLC models below:
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PDX models coming soon!
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Breast cancer PDX models
Read the latest on our PDX models
