Organoids are unique self-organising 3D microscopic structures derived from cells that represent a physiologically relevant in vitro model systems as they preserve the genomic, physiological characteristics and multicellularity of the equivalent in vivo tissue.
- Available cancer patient-derived organoids (PDOs) are 3D in vitro multicellular models established from a range of human tumour tissues
- Represent a novel in vitro platform for basic biological research and potential applications in drug testing and molecular medicine
- Use in various applications can complement existing experimental models
