TOV3133D

Derived from solid tumor of patient diagnosed with high-grade serous ovarian cancer taken pre-chemotherapy from primary disease. This cell line also formed tumors at subcutaneous sites in SCID mice. Three other cell lines from this patient are available and take at different distinct time points throughout treatment offering possible insights into the mechanisms of tumor […]

Contributors

Inventor Institute
Anne-Marie Mes-Masson and Diane Provencher Centre Hospitalier de L’université de Montréal
Cat. #: 161899
Cancer types: Ovarian cancer
Research Fields: Cancer
Organism: Human
Tissue: Ovary
Morphology: Was able to form semi-compact spheroids
Growth properties: Mixed
Primary citation: Létourneau, et al. 2012. BMC Cancer. 29,12:379. PMID: 22931248
Product description: Derived from solid tumor of patient diagnosed with high-grade serous ovarian cancer taken pre-chemotherapy from primary disease. This cell line also formed tumors at subcutaneous sites in SCID mice. Three other cell lines from this patient are available and take at different distinct time points throughout treatment offering possible insights into the mechanisms of tumor progression and evolution.
CRISPR: No
Production details: Solid ovarian tumor derived cell line was established using the scrape method where tumor tissue was scraped into a 100mm plate with complete OSE medium and maintained for 40 days. Medium was replaced weekly.
Disease: Cancer
Format: Frozen
Storage conditions: Liquid Nitrogen
Shipping conditions: Dry Ice
Growth medium: OSE medium, 10% FBS, 0.5ug/ml apmphotericin B and 50ug/ml gentamycin sulfate
Temperature: 37° C
Atmosphere: 5% O2 and 5% CO2
Biosafety level: 1
References:

Asare-Werehene, et al. 2023. Cancers (Basel). 30,15(9):2566. PMID: 37174032

Vias, et al. 2023. Elife. 11,12:e83867. PMID: 37166279

Tomas, et al. 2023. J Ovarian Res. 11, 16(1):70. PMID: 37038202

Létourneau, et al. 2012. BMC Cancer. 29,12:379. PMID: 22931248

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