HCT 116 p300 KO Rescue Cell Line
Exclusive toolThis p300 rescue cell line was generated from p300 KO Clone F5.
Contributors
| Inventor | Institute |
|---|---|
| Carlos Caldas | Cancer Research UK, Cambridge Institute |
| SKU: | 153186 |
|---|---|
| Product description: | This p300 rescue cell line was generated from p300 KO Clone F5. |
| Conditional: | Yes |
| Additional notes: | CBP was not manipulated in this cell line |
| Cellosaurus ID: | CVCL_HG30 |
| Parental cell line: | HCT 116 |
| Disease: | Cancer |
| Cat. #: | 153186 |
|---|---|
| Provenance and Ownership: | The HCT 116 p300 KO Rescue Cell Line is owned by Cancer Research UK. CancerTools supplies the HCT 116 p300 KO Rescue Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing HCT 116 p300 KO Rescue Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Continuous |
| Unit size: | 1×10^6 cells / vial |
| Cancer types: | Colorectal cancer |
| Research Fields: | Cancer; Cell biology; Drug development |
| Organism: | Human |
| Tissue: | Colon |
| Model: | Knock-In |
| Growth properties: | Adhesion properties; invasion; migration |
| Cancer Types In Detail: | Carcinoma |
| Format: | Frozen |
|---|---|
| Storage conditions: | Liquid Nitrogen |
| Shipping conditions: | Dry ice |
| Growth medium: | McCoy’s 5A medium + 10% FCS |
| Recommended controls: | HCT 116 parental line |
| Mycoplasma free: | Yes |
| Biosafety level: | 1 |
| References: |
?-HPV 5 and 8 E6 disrupt homology dependent double strand break repair by attenuating BRCA1 and BRCA2 expression and foci formation. Wallace et al. 2015. PLoS Pathog. 11(3):e1004687. PMID: 25803638. Iyer et al. 2007. Oncogene. 26(1):21-9. PMID: 16878158. Bundy et al. 2006. Cancer Res. 66(15):7606-14. PMID: 16885360. Metabolic consequences of p300 gene deletion in human colon cancer cells. p300 is required for orderly G1/S transition in human cancer cells. Krubasik et al. 2006. Br … |
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Images
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Product Images
HCT 116 p300 KO Rescue Cell Line. Early log phase
HCT 116 p300 KO Rescue Cell Line. Early log phase. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC), UK.
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