HCT 116 p300 KO [F5] Cell Line

Exclusive Tool

Cell lines available are p300 WT (HCT116), p300 KO Clone D10 (HCT116), p300 KO Clone F5 (HCT116), p300 KO Clone F2 (HCT116). Experiments conducted should be using at least 2 of the 3 KO cell lines. The best 2 KO clones are D10 and F5.

Contributors

Inventor Institute
Carlos Caldas Cancer Research UK Cambridge Institute
SKU: 153184
Product description: Cell lines available are p300 WT (HCT116), p300 KO Clone D10 (HCT116), p300 KO Clone F5 (HCT116), p300 KO Clone F2 (HCT116). Experiments conducted should be using at least 2 of the 3 KO cell lines. The best 2 KO clones are D10 and F5.
Cellosaurus ID: CVCL_HG29
Parental cell line: HCT 116
Disease: Cancer
Cat. #: 153184
Provenance and Ownership: The HCT 116 p300 KO [F5] Cell Line is owned by Cancer Research UK. CancerTools supplies the HCT 116 p300 KO [F5] Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing HCT 116 p300 KO [F5] Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Tool sub type: Continuous
Unit size: 1×10^6 cells / vial
Cancer types: Colorectal cancer
Research Fields: Cancer;Cell biology;Drug development
Organism: Human
Tissue: Colon
Model: Knock-Out
Growth properties: Adhesion properties; invasion; migration
Cancer Types In Detail: Carcinoma
Format: Frozen
Shipping conditions: Dry ice
Growth medium: McCoy’s 5A medium + 10% FCS
References:

?-HPV 5 and 8 E6 disrupt homology dependent double strand break repair by attenuating BRCA1 and BRCA2 expression and foci formation.

Wallace et al. 2015. PLoS Pathog. 11(3):e1004687. PMID: 25803638.

Iyer et al. 2007. Oncogene. 26(1):21-9. PMID: 16878158.

Bundy et al. 2006. Cancer Res. 66(15):7606-14. PMID: 16885360.

Metabolic consequences of p300 gene deletion in human colon cancer cells.

p300 is required for orderly G1/S transition in human cancer cells.

Krubasik et al. 2006. Br …

Images

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HCT 116 p300 KO [F5] Cell Line. Early log phase. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)

Related Tools for Cell lines

Cat. # Tool Name
151479 HCT 116 p300 KO [D10] Cell Line Key Info View Tool
153183 HCT 116 p300 WT Cell Line Key Info View Tool
153185 HCT 116 p300 KO [F2] Cell Line Key Info View Tool
153186 HCT 116 p300 KO Rescue Cell Line Key Info View Tool

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