ADAM15 is an active metalloproteinase with gelatinolytic and collagenolytic activity which plays a role in the wound healing process. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules.
| Inventor | Institute |
|---|---|
| Carl Blobel | Hospital for Special Surgery |
| SKU: | 152540 |
|---|---|
| Product description: | ADAM15 is an active metalloproteinase with gelatinolytic and collagenolytic activity which plays a role in the wound healing process. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. |
| Conjugation: | Unconjugated |
| Molecular weight: | ~100 kDa |
| Immunogen: | Extracellular domain fusion protein of human ADAM15 with an IgG Fc domain |
| Cat. #: | 152540 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction |
| Application: | WB |
| Target: | ADAM15 |
| Reactivity: | Human |
| Clone: | 15HUEXT |
| Host: | Rabbit |
| Class: | Polyclonal |
| Target background: | ADAM15 is an active metalloproteinase with gelatinolytic and collagenolytic activity which plays a role in the wound healing process. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | Whole serum |
| Storage conditions: | -20° C |
| Shipping conditions: | Dry ice |
| References: |
Horiuchi et al. 2003. Mol Cell Biol. 23(16):5614-24. PMID: 12897135. KrĤtzschmar et al. 1996. J Biol Chem. 271(9):4593-6. PMID: 8617717. |
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