Showing results for tumour microenvironment

Anti-p53 [Pab 246] Product

Anti-p53 clone Pab 246 recognises the tumour antigen p53, also known as p53 tumour suppressor protein or NY-CO-13. p53 is upregulated in response to DNA damage and is found in […]

Anti-SV40ST [pab 280] Product

SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.

Anti-nNav 1.5 [4G8:1G7] Product

VCSC expression has been detected in a number of tumour cell lines and has been implicated in the metastatic behaviour of breast and prostate cancer cells.

Adapted Preza et al. 2015. PLoS One. 10(4)

Anti-CD45RB [PD7/26] mAb Product

Monoclonal antibody capable of detecting CD45RB in paraffin-embedded samples, and aids in differentiating between lymphoid and non-lymphoid tumours of B-cell origin.

Anti-CD45 [2B11] Product

2B11 is widely used, in conjunction with the CD45RB antibody PD7/26, to detect white cell-derived tumours in paraffin sections.

Ding et al. 2013. PLoS One. 8(5)

Anti-CD31 (PECAM1) [JC70] mAb Product

Monoclonal antibody directed against endothelial cell marker (CD31, JC70), capable of evaluating tumour angiogenesis and angiosarcoma more effectively than anti-FVIII-Reg.

Anti-SV40LT [LP7N] Product

SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.

Anti-E2F6 [TFE61] Product

[…] is a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumour suppressor proteins.

Anti-EB1 [EB1-CL 1A11/4] Product

EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex.