Cat. #154268
Gulf War Illness Rat
Cat. #: 154268
Sub-type: Mouse
Availability: 8-10 weeks
Disease: Gulf War Illness
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Laxmikant Deshpande
Institute: Virginia Commonwealth University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: Gulf War Illness Rat
- Tool sub type: Mouse
- Disease: Gulf War Illness
- Description: Repeated low-dose organophosphate diisopropyl fluorophosphate (DFP) exposre leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness
- Phenotype: Gulf War Illness
- Zygosity: unknown
- Production details: Rats were injected s.c. with 400 Âľg/kg DFP once-daily for 5 days
- Additional notes: Male Sprague-Dawley Rats
Target Details
- Target: acetylcholinesterase
References
- Phillips et al. 2019. Toxicol Sci. 169(2):567-578. PMID: 30859209.
- Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness.
- Phillips et al. 2018. Mil Med. 183(suppl_1):552-555. PMID: 29635560.
- Chronic Neurological Morbidities and Elevated Hippocampal Calcium Levels in a DFP-Based Rat Model of Gulf War Illness.
- Phillips et al. 2016. Neurotoxicology. 52:127-33. PMID: 26619911.
- Repeated low-dose organophosphate DFP exposure leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness.
