Cat. #156409
R-3327-MAT-Lu cell line
Cat. #: 156409
Unit size: 1x10^6 cells / vial
Availability: 10-12 weeks
Disease: Cancer
Model: Cancer Model
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: John Isaacs
Institute: Johns Hopkins University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: R-3327-MAT-Lu cell line
- Cancer: Genitourinary cancer
- Cancers detailed: Prostate
- Research fields: Cancer;Drug development
- Disease: Cancer
- Model: Cancer Model
- Description: This cell line was derived from the "H" subline and upon passage to the AT-1 subline (JHU-29) of the parental R3327 tumor. The "H" subline is a heterogeneous cell line as it is comprised of androgen-dependent and androgen-independent tumor cells. Passing this AT-1 sublinein intactmale rats allowed for the cloning of androgen-independent cell lines which gave rise to a fast-growing metastatic, anaplastic tumor (MAT) cell line which was further characterized to be highly metastatic to the lung (MAT-Lu). This cell line is a valuable model for the studying prostate malignancies both in vitro, and in vivo.DM 3852
- Cellosaurus id: CVCL_3847
Target Details
- Target: Metastatic anaplastic tumor that is highly metastatic in the lung
Handling
- Format: Frozen
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
References
- Isaacs et al. 1988. Prostate. 13(2):165-88. PMID: 3174494.
- Isaacs et al. 1986. Prostate. 9(3):261-81. PMID: 3774632.
