#162003

Melan-p53-2 cell line

Cat. #162003

Melan-p53-2 cell line

Cat. #: 162003

Organism: Mouse

Tissue: Skin

Disease: Non-cancer

Model: Immortalised non-cancerous cell lines

£575.00

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Contributor

Inventor: Elena Sviderskaya

Institute: St. George's University London

Primary Citation: Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20;94(6):446-54. PMID: 11904317

Tool Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Melan-p53-2 cell line
  • Organism: Mouse
  • Gender: Unspecified
  • Tissue: Skin
  • Disease: Non-cancer
  • Morphology: Small, oval-fusiform
  • Model: Immortalised non-cancerous cell lines
  • Description: The melan-p53-1, -2 and -3 cell lines are immortal melanocyte cell lines derived from the skin of neonatal Tp53–/– C57BL/6J mice. The expression of Ink4a in these cells is supressed and Arf expression is diminished. These cells are visibly pigmented and display morphology typical of normal melanocytes and can be useful in studying the role of p53 in melanocytes.
  • Application: Melanocyte cell biology
  • Biosafety level: BSL1

Applications

  • Application: Melanocyte cell biology

Handling

  • Growth medium: RPMI + FBS (10%) + TPA (200 nM) + cholera toxin (CT) (200 pM)
  • Storage conditions: liquid N2

References

  • Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20
  • 94(6):446-54. PMID: 11904317