Cat. #161991
Melan-a4 cell line
Cat. #: 161991
Organism: Mouse
Tissue: Skin
Disease: Non-cancer
Model: Immortalised non-cancerous cell lines
£575.00
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Contributor
Inventor: Elena Sviderskaya
Institute: St. George's University London
Primary Citation: Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20;94(6):446-54. PMID: 11904317
Tool Details
*FOR RESEARCH USE ONLY
- Name: Melan-a4 cell line
- Organism: Mouse
- Tissue: Skin
- Disease: Non-cancer
- Morphology: Small, oval-fusiform
- Model: Immortalised non-cancerous cell lines
- Description: The melan-a3 and -a4 melanocyte cell lines were derived from the skin of neonatal C57BL/6J mixed mice. These cells are visibly pigmented and display morphology typical of normal melanocytes. These melanocytes can be used as a model of normal skin melanocytes in studies focussing on skin cancers and melanomas. They are also a useful tool for studies of pigmentation genetics.
- Application: Melanocyte cell biology
Applications
- Application: Melanocyte cell biology
Handling
- Growth medium: RPMI + FBS (10%) + TPA (200 nM) + cholera toxin (CT) (200 pM)
- Storage conditions: liquid N2
References
- Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20
- 94(6):446-54. PMID: 11904317
