Zinc transporter ZIP4 is a transmembrane protein which in humans is encoded by the SLC39A4 gene. ZIP4 is overexpressed in human pancreatic cancer and contributes to tumor progression by accumulation of intracellular zinc and stimulation of cell proliferation, endothelial mesenchymal transition and cancer progression.
| Inventor | Institute |
|---|---|
| RubĂŠn Vicente, Pilar Rivera | Universitat Pompeu Fabra |
| Cat. #: | 161642 |
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| Tool sub type: | Primary antibody |
| Cancer types: | Pancreatic cancer |
| Research Fields: | Cancer |
| Application: | Western Blottting, Immunostaining |
| Target: | Zinc Transporter ZIP4 |
| Reactivity: | Human |
| Clone: | 33 |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Li et al. 2007. Proc Natl Acad Sci U S A. 104(47):18636-41. PMID 18003899. |
| Product description: | Zinc transporter ZIP4 is a transmembrane protein which in humans is encoded by the SLC39A4 gene. ZIP4 is overexpressed in human pancreatic cancer and contributes to tumor progression by accumulation of intracellular zinc and stimulation of cell proliferation, endothelial mesenchymal transition and cancer progression. |
|---|---|
| Isotype: | IgG |
| Target background: | Zinc transporter ZIP4 is a transmembrane protein which in humans is encoded by the SLC39A4 gene. ZIP4 is overexpressed in human pancreatic cancer and contributes to tumor progression by accumulation of intracellular zinc and stimulation of cell proliferation, endothelial mesenchymal transition and cancer progression. Thus, overexpression of ZIP4 is considered a malignant factor for pancreatic cancer progression. |
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| Shipping conditions: | Dry ice |
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| References: |
Li et al. 2007. Proc Natl Acad Sci U S A. 104(47):18636-41. PMID 18003899. |
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