Anti-UCP1 [Vab12 P4B12*A12]
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
Contributors
| Inventor | Institute |
|---|---|
| Ayham Alnabulsi | Vertebrate Antibodies Limited |
| SKU: | 152686 |
|---|---|
| Product description: | UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Ovalbumin-conjugated synthetic peptide – (10 amino acids) derived from the middle polypeptide region of human UCP1. The exact sequence is proprietary. |
| Myeloma used: | P3X63Ag8.653 |
| Cat. #: | 152686 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell signaling and signal transduction;Metabolism |
| Application: | ELISA ; IHC ; WB |
| Target: | Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1) |
| Reactivity: | Human |
| Clone: | Vab12 P4B12*A12 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
The expression of brown fat-associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis. The expression of brown fat associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis. Alnabulsi et al. 2019. Int J Cancer. |
|---|
Images
View Gallery
Product Images
d0a83e41-5685-480a-b78a-951088666e25.jpg
Immunohistochemical staining of human breast cancer tissue shows cytoplasmic positivity. IHC was performed on formalin-fixed; paraffin-embedded tissue sections.
