Cat. #161719
Anti-TIAM1 [4E7-b1]
Cat. #: 161719
Sub-type: Primary antibody
Target: TIAM1
Class: Monoclonal
Application: WB(1:1000), IP
Reactivity: human; mouse; rat
Host: mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jihong Bai, PhD
Institute: Fred Hutichinson Cancer Center
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-TIAM1 [4E7-b1]
- Clone: 4E7-b1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: No
- Molecular weight: 178 kDa
- Reactivity: human; mouse; rat
- Host: mouse
- Application: WB(1:1000), IP
- Description: T-lymphoma invasion and metastasis-inducing protein 1 (TIAM1) is a protein coding gene, specifically for RAC-1. RAC-1 is a specific guanine nucleotide exchange factor (GEF). GEFs mediate the exchange of guanosine diphosphate (GDP) for guanosine triphosphate (GTP). This gene thus regulates RAC1 signaling pathways that affect cell shape, migration, adhesion, growth, survival, and polarity, as well as influencing actin cytoskeletal formation, endocytosis, and membrane trafficking. Diseases associated with TIAM1 include lymphoma and Wolf-Hirschhorn Syndrome.
- Immunogen: Recombinant TIAM1 GEF domain (mouse 1029-1418)
Target Details
- Target: TIAM1
- Molecular weight: 178 kDa
- Target background: recombinant T-lymphoma invasion and metasis-inducing protein 1 (TIAM1)
Applications
- Application: WB(1:1000), IP
Handling
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: 4° C
References
- No publication, validated internally
