Anti-TAL1 [BTL73]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-TAL1 [BTL73]
• Research fields: Cancer;Cell biology;Developmental biology;Genetics;Stem cell biology
• Clone: BTL73
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Reactivity: Human
• Host: Mouse
• Application: ChIP ; ELISA ; IHC ; WB
• Description: Monoclonal antibody which stains 3 forms of TAL1 in the cytoplasm and nuclei of cells.
• Immunogen: TAL-1 recombinant protein
• Immunogen uniprot id: P17542
• Isotype: IgG1
• Myeloma used: P3/NS1/1-Ag4.1

Target Details

• Target: TAL1
• Target background: Monoclonal antibody which stains 3 forms of TAL1 in the cytoplasm and nuclei of cells.

Applications

• Application: ChIP ; ELISA ; IHC ; WB

Handling

• Format: Liquid
• Concentration: 1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
• Shipping conditions: Dry ice

References

• Christophersen et al. 2017. Sci Rep. 7:40451. PMID: 28084402.
• Farrell et al. 2011. Blood. 117(18):4935-45. PMID: 21385855.
• A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression.
• Goardon et al. 2002. Blood. 100(2):491-500. PMID: 12091340.
• Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation.
• Delabesse et al. 1998. Br J Haematol. 102(2):449-57. PMID: 9695959.
• TAL1 expression does not occur in the majority of T-ALL blasts.
• Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.
• Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.
• Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.
• Expression of TAL-1 proteins in human tissues.