Monoclonal antibody which stains 3 forms of TAL1 in the cytoplasm and nuclei of cells.
| Inventor | Institute |
|---|---|
| Karen Pulford | University of Oxford |
| Cat. #: | 151415 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Developmental biology;Genetics;Stem cell biology |
| Application: | ChIP ; ELISA ; IHC ; WB |
| Target: | TAL1 |
| Reactivity: | Human |
| Clone: | BTL73 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Monoclonal antibody which stains 3 forms of TAL1 in the cytoplasm and nuclei of cells. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | TAL-1 recombinant protein |
| Immunogen Uniprot ID: | P17542 |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Monoclonal antibody which stains 3 forms of TAL1 in the cytoplasm and nuclei of cells. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | Store at -20° C frozen. Avoid repeated freeze / thaw cycles |
| Shipping conditions: | Dry ice |
| References: |
Christophersen et al. 2017. Sci Rep. 7:40451. PMID: 28084402. Farrell et al. 2011. Blood. 117(18):4935-45. PMID: 21385855. A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. Goardon et al. 2002. Blood. 100(2):491-500. PMID: 12091340. Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation. Delabesse et al. 1998. Br J Haematol. 102(2):449-57. PMID: 9695959. TAL1 expression does not occur in the majority of T-ALL blasts. Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670. Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain. Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471. Expression of TAL-1 proteins in human tissues. |
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