Cat. #153338
Anti-SV40T [PAB416]
Cat. #: 153338
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: N-terminal domain of SV40 large and small T-antigen
Class: Monoclonal
Application: IHC ; IF ; IP ; WB
Reactivity: Virus
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Lionel Crawford
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-SV40T [PAB416]
- Cancers detailed: Broadly Applicable;Polyoma
- Research fields: Microbiology
- Clone: PAb416
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 94 kDa
- Strain: Balb/c
- Reactivity: Virus
- Host: Mouse
- Application: IHC ; IF ; IP ; WB
- Description: Monoclonal antibody directed at large T antigen of SV40, valuable for investigation into other SV40 tumour antigens and polyomaviruses. Background and Research Application Anti-SV40T which binds to the large T antigen of the Simian oncogenic polyoma virus (SV40). Both the Simian virus (SV40) large T and small T antigens are encoded by the early region of the SV40 genome. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins. Large T is cap...
- Immunogen: SV40 transformed mouse cells
- Immunogen uniprot id: P03070
- Isotype: IgG2a
- Myeloma used: P3/NS1/1-Ag4.1
- Recommended controls: SV80 or SV-T2 cells
Target Details
- Target: N-terminal domain of SV40 large and small T-antigen
- Molecular weight: 94 kDa
- Tissue cell line specificity: SV80 or SV-T2 cells
- Target background: Monoclonal antibody directed at large T antigen of SV40, valuable for investigation into other SV40 tumour antigens and polyomaviruses. Background and Research Application Anti-SV40T which binds to the large T antigen of the Simian oncogenic polyoma virus (SV40). Both the Simian virus (SV40) large T and small T antigens are encoded by the early region of the SV40 genome. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins. Large T is ca...
Applications
- Application: IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Dry ice
References
- Tanaka et al. 2018. J Vet Med Sci. 80(9):1400-1406. PMID: 30012933.
- Pelletier et al. 2018. Histopathology. 73(1):162-166. PMID: 29430700.
- Rigatti et al. 2016. mSphere. 1(6):. PMID: 28028546.
- Toptan et al. 2016. JCI Insight. 1(2):. PMID: 27034991.
- Chiaravalli et al. 2013. J Clin Pathol. 66(1):44-9. PMID: 23012397.
- Sabatier et al. 2005. J Clin Pathol. 58(4):429-31. PMID: 15790713.
- Immunodetection of SV40 large T antigen in human central nervous system tumours.
- Radhakrishnan et al....
