Antibody for the human primase p48, or human p48 protein kinase, of PRIM2. Applicable to numerous tumour types – its role in cancer is intimately linked to its essential function in DNA replication and genome maintenance.
| Institute |
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| Helmholtz Munich Core Facility Monoclonal Antibodies |
| Cat. #: | 162377 |
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| Tool sub type: | Primary antibody |
| Research Fields: | Cancer;Cell biology |
| Application: | WB |
| Target: | Human primase p48 |
| Reactivity: | Human |
| Clone: | PRI-8G10 |
| Host: | Rat |
| Class: | Monoclonal |
| Primary citation: | Weisshart et al. 2000. J. Biol. Chem. 275: 17328-17337. PMID: 10747950 |
| Alternate name: | Anti human primase p48 monoclonal antibody (clone PRI-8G10) |
|---|---|
| Product description: | Antibody for the human primase p48, or human p48 protein kinase, of PRIM2. Applicable to numerous tumour types – its role in cancer is intimately linked to its essential function in DNA replication and genome maintenance. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Recombinant primase p48 subunit |
| Target background: | Primase p48, also known as PRIM1 or DNA primase subunit 1, is the catalytic subunit of eukaryotic DNA primase. It partners with primase p58 (PRIM2) to form the functional primase heterodimer. As such, its role in cancer is intimately linked to its essential function in DNA replication and genome maintenance. |
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| References: |
Weisshart et al. 2000. J. Biol. Chem. 275: 17328-17337. PMID: 10747950 |
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