Cat. #151787
Anti-PDGFR alpha [PDGFR-H7A]
Cat. #: 151787
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: PDGFR alpha, platelet-derived growth factor receptor, alpha polypeptide.
Class: Monoclonal
Application: IP
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jacqueline Cordell
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-PDGFR alpha [PDGFR-H7A]
- Research fields: Cell signaling and signal transduction;Developmental biology;Disease (not cancer)
- Clone: PDGFR-H7A
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IP
- Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
- Immunogen: Recombinant protein corresponding to amino acids 1 to 78 of human PDGFRA
- Isotype: IgG1 lambda
- Myeloma used: NS0
- Recommended controls: Human Hela cell line
Target Details
- Target: PDGFR alpha, platelet-derived growth factor receptor, alpha polypeptide.
- Tissue cell line specificity: Human Hela cell line
- Target background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the Fn receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Applications
- Application: IP
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
