Cat. #152744
Anti-PAT4 [PAT4/157/D10]
Cat. #: 152744
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: PAT4 (SLC36A4)
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Helen Turley ; Deborah Goberdhan
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-PAT4 [PAT4/157/D10]
- Research fields: Cell signaling and signal transduction;Metabolism
- Clone: PAT4/157/D10
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: ~ 60 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: The anti-PAT4 [PAT-4/157/D10] antibody is a highly specific mouse monoclonal antibody against PAT4. Members of the proton-assisted amino-acid transporter (PAT) or solute-linked carrier 36 (SLC36) family have been identified as positive regulators of growth and mTORC1 signalling in flies.These effects were shown to be conserved by characterisation of the two ubiquitously transcribed human PATs, PAT1 (SLC36A1) and PAT4 (SLC36A4). PAT4 is upregulated in aggressive forms of colorectal cancer and a possible biomarker.
- Immunogen: Antigenic amino acid sequence within the N-terminus of PAT4 (REELDMDVMRPLINE-C).
- Isotype: IgG1
- Myeloma used: NS0
- Recommended controls: 786-O human renal cancer cells
Target Details
- Target: PAT4 (SLC36A4)
- Molecular weight: ~ 60 kDa
- Tissue cell line specificity: 786-O human renal cancer cells
- Target background: The anti-PAT4 [PAT-4/157/D10] antibody is a highly specific mouse monoclonal antibody against PAT4. Members of the proton-assisted amino-acid transporter (PAT) or solute-linked carrier 36 (SLC36) family have been identified as positive regulators of growth and mTORC1 signalling in flies.These effects were shown to be conserved by characterisation of the two ubiquitously transcribed human PATs, PAT1 (SLC36A1) and PAT4 (SLC36A4). PAT4 is upregulated in aggressive forms of colorectal cancer and a possible biomarker.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
