Cat. #152613
Anti-p53 [V5P4H6*B3]
Cat. #: 152613
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: p53
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Zebrafish
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-p53 [V5P4H6*B3]
- Cancer: Other
- Cancers detailed: Broadly Applicable
- Research fields: Apoptosis and autophagy;Cancer;Cell biology;Genetics
- Clone: V5P4H6*B3
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Zebrafish
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: p53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of B...
- Immunogen: Ovalbumin-conjugated synthetic peptide KLMVKDEGRS (C-terminal sequence)
- Isotype: IgG1 kappa
- Recommended controls: WB - whole Zebrafish lysate; IHC- Zebrafish embryo
Target Details
- Target: p53
- Tissue cell line specificity: WB - whole Zebrafish lysate; IHC- Zebrafish embryo
- Target background: p53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of B...
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -20° C
- Shipping conditions: Shipping at 4° C