NCAM, also known as CD56, is a homophillic binding glycoprotein present on a variety of neural cells including neurons, glia, skeletal muscle and natural killer cells.
| Inventor | Institute |
|---|---|
| John Kemshead | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 152631 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Cell signaling and signal transduction;Neurobiology;Stem cell biology |
| Application: | IF ; WB |
| Target: | Neural Cell Adhesion Molecule (NCAM; CD56) |
| Reactivity: | Human |
| Clone: | UJ13A |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Neural Cell Adhesion Molecule; NCAM; CD56 Antigen; MSK39 |
|---|---|
| Product description: | NCAM, also known as CD56, is a homophillic binding glycoprotein present on a variety of neural cells including neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell-cell adhesion, neurite outgrowth, synatptic plasticity, learning and memory and in the development of the nervous system. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 180 kDa, 160 kDa, 120 kDa |
| Immunogen: | 16 week human foetal brain |
| Target background: | NCAM, also known as CD56, is a homophillic binding glycoprotein present on a variety of neural cells including neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell-cell adhesion, neurite outgrowth, synatptic plasticity, learning and memory and in the development of the nervous system. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Patel et al. 1989. Int J Cancer. 44(6):1062-8. PMID: 2558078. Patel et al. 1989. Br J Cancer. 60(6):861-6. PMID: 2481486. Monoclonal antibody 3F8 recognises the neural cell adhesion molecule (NCAM) in addition to the ganglioside GD2. Monoclonal antibody UJ13A recognizes the neural cell adhesion molecule (NCAM). Moss et al. 1988. Lung Cancer. 4, 76-78. Allan et al. 1983. Int J Cancer. 31(5):591-8. PMID: 6852977. Biological characterization and clinical applications of a monoclonal antibody recognizing an antigen restricted to neuroectodermal tissues. |
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