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#154752

Anti-MHC class II HLA-DQ [SPVL3]

Cat. #154752

Anti-MHC class II HLA-DQ [SPVL3]

Cat. #: 154752

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: MHC class II HLA-DQ

Class: Monoclonal

Application: FACS ; IHC ; IP

Reactivity: Human ; Pig

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Netherlands Cancer Institute

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-MHC class II HLA-DQ [SPVL3]
  • Research fields: Cell signaling and signal transduction;Immunology
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human ; Pig
  • Host: Mouse
  • Application: FACS ; IHC ; IP
  • Description: HLA-DQ (DQ) is a cell surface receptor protein found on antigen presenting cells. It is an Î?Î? heterodimer of type MHC class II. The Î? and Î? chains are encoded by two loci, HLA-DQA1 and HLA-DQB1, that are adjacent to each other on chromosome band 6p21.3. Both Î?-chain and Î?-chain vary greatly. A person often produces two Î?-chain and two Î?-chain variants and thus 4 isoforms of DQ.
  • Immunogen: Cloned cytotoxic T lymphocytes.
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: MHC class II HLA-DQ
  • Target background: HLA-DQ (DQ) is a cell surface receptor protein found on antigen presenting cells. It is an a? heterodimer of type MHC class II. The a and ? chains are encoded by two loci, HLA-DQA1 and HLA-DQB1, that are adjacent to each other on chromosome band 6p21.3. Both a-chain and ?-chain vary greatly. A person often produces two a-chain and two ?-chain variants and thus 4 isoforms of DQ.

Applications

  • Application: FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

References

  • te Velde et al. 1988. J Immunol. 140(5):1548-54. PMID: 3279117.
  • Spits et al. 1984. Eur J Immunol. 14(4):299-304. PMID: 6609821.
  • Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.

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