Cat. #153992
Anti-LRP1[5A6]
Cat. #: 153992
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Low density lipoprotein receptor-related protein-1, light chain
Class: Monoclonal
Application: WB ; IHC ; IF
Reactivity: Mouse ; Rat ; Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: University of Maryland
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-LRP1[5A6]
- Alternate name: LRP1, Low density lipoprotein receptor-related protein 1, apolipoprotein E receptor (APOER), cluster of differentiation 91 (CD91), alpha-2-macroglobulin receptor (A2MR)
- Research fields: Cell signaling and signal transduction;Genetics;Neurobiology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 85/515/600 kDa
- Reactivity: Mouse ; Rat ; Human
- Host: Mouse
- Application: WB ; IHC ; IF
- Description: LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Functionally, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus.
- Immunogen: recombinant human fragment; 85 kDa LRP
- Isotype: IgG2b
Target Details
- Target: Low density lipoprotein receptor-related protein-1, light chain
- Molecular weight: 85/515/600 kDa
- Tissue cell line specificity: Mouse
- Target background: LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Fnly, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus.
Applications
- Application: WB ; IHC ; IF
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Strickland et al. 1990. J Biol Chem. 265(29):17401-4. PMID: 1698775.
- Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multiFn receptor.
