Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias. Lewis X is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and the study of myeloid differentiation.
| Inventor | Institute |
|---|---|
| Karen Pulford | University of Oxford |
| Cat. #: | 151350 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Immunology |
| Application: | FACS ; IHC ; IF ; IP ; WB |
| Target: | Lewis X (CD15) |
| Reactivity: | Human |
| Clone: | By87a |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX |
|---|---|
| Product description: | Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias. Lewis X is commonly used in the diagnosis of Hodgkin's disease. It can also be used for analysis of myeloid leukaemias and the study of myeloid differentiation. |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Immunogen: | B cell lymphoma cells |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias. Lewis X is commonly used in the diagnosis of Hodgkin's disease. It can also be used for analysis of myeloid leukaemias and the study of myeloid differentiation. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Dorfman et al. 1986. Am J Pathol. 123(3):508-19. PMID: 3717303. An evaluation of the utility of anti-granulocyte and anti-leukocyte monoclonal antibodies in the diagnosis of Hodgkin's disease. |
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