Anti-Leu2 [X107]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-Leu2 [X107]
• Alternate name: CD8a Molecule; T-Lymphocyte Differentiation Antigen T8/Leu-2; CD8 Antigen; Alpha Polypeptide (P32); MAL; T-Cell Surface Glycoprotein CD8 Alpha Chain; Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen; T-Cell Antigen Leu2; T8 T-Cell Antigen; CD8a Antigen; Leu2; P32
• Research fields: Immunology;Stem cell biology
• Clone: X107
• Class: Monoclonal
• Conjugation: Unconjugated
• Reactivity: Human
• Host: Mouse
• Application: FACS ; IHC
• Description: Leu-2 (CD8) is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells which make up 30% of circulating T cells. X107 may be used to detect these cells in tissue sections and also their neoplastic counterparts.
• Immunogen: Synthetic peptide ( the 13 c-terminal residues of the cytoplasmic domain of human CD8a)
• Isotype: Not Known
• Myeloma used: P3/NS1/1-Ag4.1

Target Details

• Target: Leu2 (CD8)
• Target background: Leu-2 (CD8) is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells which make up 30% of circulating T cells. X107 may be used to detect these cells in tissue sections and also their neoplastic counterparts.

Applications

• Application: FACS ; IHC

Handling

• Format: Liquid
• Concentration: 1 mg/ml
• Unit size: 100 ug
• Storage buffer: RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
• Storage conditions: -15° C to -25° C
• Shipping conditions: Dry ice

References

• Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. p 1076. ISBN-13: 978-0192618672