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#151437

Anti-Leu2 [BU88]

Cat. #151437

Anti-Leu2 [BU88]

Cat. #: 151437

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Leu2 (CD8)

Class: Monoclonal

Application: FACS ; IHC

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Roy Jefferis

Institute: University of Birmingham

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Leu2 [BU88]
  • Research fields: Immunology;Stem cell biology
  • Clone: BU88
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC
  • Description: BU88 may be used for the detection of immunoregulatory T cell subset imbalance in autoimmune and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma and T4/T8 ratios in rheumatoid arthritis, multiple sclerosis, etc.
  • Immunogen: CD8 enriched peripheral blood lymphocytes
  • Isotype: IgG1
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Leu2 (CD8)
  • Target background: Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells.

Applications

  • Application: FACS ; IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

References

  • Kishimoto T. et al. (Eds.) 1997. Leukocyte Typing VI. Garland Publishing Inc. ISBN-13: 978-0815327455
  • Leukocyte Typing VI. Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997)
  • Langermans et al. 2000. J Med Primatol. 29(6):397-401. PMID: 11168830.
  • Reactivity of human T-lymphocyte-specific antibodies with peripheral blood mononuclear cells and spleen of Aotus azarae ssp. boliviensis (owl monkey).

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