#151202

Anti-Keratin18 [LC18N]

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Cat. #151202

Anti-Keratin18 [LC18N]

Cat. #: 151202

Unit size: 100 ug

Availability: 3-4 weeks

Target: Keratin 18

Class: Monoclonal

Application: IHC ; IF ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Birgit Lane

Institute: University of Dundee

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Keratin18 [LC18N]
  • Research fields: Cell signaling and signal transduction
  • Clone: LC18N
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; IF ; WB
  • Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas.
  • Immunogen: Synthetic pepide of N terminus of human keratin 18 (NH2- SFTTRSTFSC)
  • Isotype: IgG1
  • Recommended controls: HT29 cell line, skin, breast or lung carcinoma

Target Details

  • Target: Keratin 18
  • Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas.

Applications

  • Application: IHC ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Unit size: 100 ug
  • Storage buffer: DMEM + 5% FCS
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Porter RM et al. Lab Invest. 2000 Nov
  • 80(11):1701-10. PMID: 1109253