Cat. #151202
Anti-Keratin18 [LC18N]
Cat. #: 151202
Unit size: 100 ug
Availability: 3-4 weeks
Target: Keratin 18
Class: Monoclonal
Application: IHC ; IF ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Birgit Lane
Institute: University of Dundee
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Keratin18 [LC18N]
- Research fields: Cell signaling and signal transduction
- Clone: LC18N
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IF ; WB
- Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas.
- Immunogen: Synthetic pepide of N terminus of human keratin 18 (NH2- SFTTRSTFSC)
- Isotype: IgG1
- Recommended controls: HT29 cell line, skin, breast or lung carcinoma
Target Details
- Target: Keratin 18
- Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas.
Applications
- Application: IHC ; IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: DMEM + 5% FCS
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Porter RM et al. Lab Invest. 2000 Nov
- 80(11):1701-10. PMID: 1109253
