#151164

Anti-Involucrin [SY8]

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Cat. #151164

Anti-Involucrin [SY8]

Cat. #: 151164

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Involucrin

Class: Monoclonal

Application: IHC ; IF ; IP ; WB

Reactivity: Dog ; Human ; Pig ; Primate

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Fiona Watt

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Involucrin [SY8]
  • Research fields: Cancer;Cell signaling and signal transduction
  • Clone: SY8
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 66-170 kDa
  • Strain: Balb/c
  • Reactivity: Dog ; Human ; Pig ; Primate
  • Host: Mouse
  • Application: IHC ; IF ; IP ; WB
  • Description: SY8 is useful for studies of changes in involucrin expression in pathological studies.
  • Immunogen: Purified involucrin from human keratinocytes.
  • Isotype: IgG1
  • Myeloma used: P3X63Ag8
  • Recommended controls: MCF-7 cells. Localized to upper spinous and granular layers in normal skin.

Target Details

  • Target: Involucrin
  • Molecular weight: 66-170 kDa
  • Tissue cell line specificity: MCF-7 cells. Localized to upper spinous and granular layers in normal skin.
  • Target background: Involucrin is a protein precursor of the epidermal cornified envelope and a differentiation marker of human keratinocytes.

Applications

  • Application: IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-Involucrin, Recombinant [SY5]

References

  • Howie et al. 2011. PLoS Pathog. 7(8):e1002211. PMID: 21901101.
  • Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.
  • Hudson et al. 1992. Hybridoma. 11(3):367-79. PMID: 1500072.
  • Characterisation of eight monoclonal antibodies to involucrin.