Cat. #151164
Anti-Involucrin [SY8]
Cat. #: 151164
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Involucrin
Class: Monoclonal
Application: IHC ; IF ; IP ; WB
Reactivity: Dog ; Human ; Pig ; Primate
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Fiona Watt
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Involucrin [SY8]
- Research fields: Cancer;Cell signaling and signal transduction
- Clone: SY8
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 66-170 kDa
- Strain: Balb/c
- Reactivity: Dog ; Human ; Pig ; Primate
- Host: Mouse
- Application: IHC ; IF ; IP ; WB
- Description: SY8 is useful for studies of changes in involucrin expression in pathological studies.
- Immunogen: Purified involucrin from human keratinocytes.
- Isotype: IgG1
- Myeloma used: P3X63Ag8
- Recommended controls: MCF-7 cells. Localized to upper spinous and granular layers in normal skin.
Target Details
- Target: Involucrin
- Molecular weight: 66-170 kDa
- Tissue cell line specificity: MCF-7 cells. Localized to upper spinous and granular layers in normal skin.
- Target background: Involucrin is a protein precursor of the epidermal cornified envelope and a differentiation marker of human keratinocytes.
Applications
- Application: IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
Related Tools
- Related tools: Anti-Involucrin, Recombinant [SY5]
References
- Howie et al. 2011. PLoS Pathog. 7(8):e1002211. PMID: 21901101.
- Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.
- Hudson et al. 1992. Hybridoma. 11(3):367-79. PMID: 1500072.
- Characterisation of eight monoclonal antibodies to involucrin.
