Monoclonal antibody with use studying inhibition of cellular adhesion.
| Inventor | Institute |
|---|---|
| Joyce Taylor-Papadimitriou | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151109 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Cancer |
| Application: | FACS ; IHC ; IF ; Fn |
| Target: | Integrin a3 (CD49c) |
| Reactivity: | Human |
| Clone: | IA3 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Monoclonal antibody with use studying inhibition of cellular adhesion. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 180-220 kDa |
| Immunogen: | Transfected human breast epithelial cell line MTSV1-7, hygromycin resistant. |
| Immunogen Uniprot ID: | P26006 |
| Myeloma used: | P3X63Ag8.653 |
| Target background: | Monoclonal antibody with use studying inhibition of cellular adhesion. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | Store at -20° C frozen. Avoid repeated freeze / thaw cycles |
| Shipping conditions: | Dry ice |
| References: |
Tremblay et al. 2017. Sci Rep. 7:46574. PMID: 28422167. Tremblay et al. 2017. Sci Rep. 7:46574. PMID: 28422167. Seltmann et al. 2015. J Invest Dermatol. 135(6):1609-1620. PMID: 25668239. Seltmann et al. 2015. J Invest Dermatol. 135(6):1609-20. PMID: 25668239. Keratins Stabilize Hemidesmosomes through Regulation of ?4-Integrin Turnover. Stawikowski et al. 2014. J Biol Chem. 289(31):21591-604. PMID: 24958723. Glycosylation modulates melanoma cell a2?1 and a3?1 integrin interactions with type IV collagen. Pytlk et al. 2009. Biomaterials. 30(20):3415-27. PMID: 19362364. The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering. Turner et al. 2006. Circulation. 114(8):820-9. PMID: 16908762. Alpha2(VIII) collagen substrata enhance endothelial cell retention under acute shear stress flow via an alpha2beta1 integrin-dependent mechanism: an in vitro and in vivo study. Berdichevsky et al. 1994. J Cell Sci. 107 ( Pt 12):3557-68. PMID: 7535787. Branching morphogenesis of human mammary epithelial cells in collagen gels. |
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