ICAM-3 is the major ligand for LFA-1 (CD11a/CD18) in the resting state.
| Inventor | Institute |
|---|---|
| Jacqueline Cordell | University of Oxford |
| Cat. #: | 151366 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Cell signaling and signal transduction;Immunology |
| Application: | FACS ; IHC ; IP ; WB |
| Target: | ICAM3 (CD50) |
| Reactivity: | Human |
| Clone: | CG106 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Intercellular Adhesion Molecule 3; ICAM-3; ICAM-R; CDW5; CD5 |
|---|---|
| Product description: | ICAM-3 is the major ligand for LFA-1 (CD11a/CD18) in the resting state. ICAM-3 may play a key role in initiating immune responses. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | T-lymphoblastic cells |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | ICAM-3 is the major ligand for LFA-1 (CD11a/CD18) in the resting state. ICAM-3 may play a key role in initiating immune responses. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Bossy D et al. 1995. Eur. J. Immunol. 25(2):459-65. PMID: 7875209 Cordell JL et al. 1994. J Clin Pathol 47:143-7. PMID: 8132828 Doussis-Anagnostopoulou I et al. 1993. Am J Pathol 143:1040-3. PMID: 8214000 Holness CL et al. 1995. J. Biol. Chem. 270(2): 877-84. PMID: 7822326 |
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