ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium.
| Inventor | Institute |
|---|---|
| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151036 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology;Stem cell biology;Tissue-specific biology |
| Application: | FACS ; IHC ; IP ; Fn |
| Target: | ICAM1 (CD54) |
| Reactivity: | Human |
| Clone: | 15.2 |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Dransfield et al. 1992. J Cell Biol. 116(6):1527-35. PMID: 1541641 |
| Alternate name: | Intercellular Adhesion Molecule 1; Major Group Rhinovirus Receptor; ICAM-1; Cell Surface Glycoprotein P3.58; Human Rhinovirus Receptor; P3.58; CD54; BB2 |
|---|---|
| Product description: | ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 85-115 kDa |
| Immunogen: | Rheumatoid synovial cells and human monocytes. |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -20° C |
| Shipping conditions: | Dry ice |
| References: |
Vsquez et al. 2016. Microbes Infect. :. PMID: 27717894. Novotny et al. 2016. Cell Microbiol. :. PMID: 26857242. El-Bikai et al. 2010. Arthritis Res Ther. 12(5):R201. PMID: 20977750. Conway et al. 2010. Am J Physiol Heart Circ Physiol. 298(2):H367-74. PMID: 19915176. Lauriello et al. 2005. Acta Otorhinolaryngol Ital. 25(5):284-91. PMID: 16602327. Stanley et al. 2000. Biochem J. 351(Pt 1):79-86. PMID: 10998349. Dransfield et al. 1992. J Cell Biol. 116(6):1527-35. PMID: 1541641. |
|---|
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151027 | Anti-HSVICP8 [10A3] |
Key Info
Anti-HSVICP8 [10A3]
|
View Tool | |||||||||||||||||||
| 151035 | Anti-CD8 [14] mAb |
Key Info
Anti-CD8 [14] mAb
|
View Tool | |||||||||||||||||||
| 151039 | Anti-Integrin aVb3 [23C6] |
Key Info
Anti-Integrin aVb3 [23C6]
|
View Tool | |||||||||||||||||||
| 151018 | Anti-Mos [R38.1] |
Key Info
Anti-Mos [R38.1]
|
View Tool | |||||||||||||||||||
| 151020 | Anti-CyclinB1 [V143.1] |
Key Info
Anti-CyclinB1 [V143.1]
|
View Tool | |||||||||||||||||||
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.