Cat. #162062
Anti-HSP90 beta [MBH90B]
Cat. #: 162062
Sub-type: Primary antibody
Target: beta forms of heat shock protein 90 (HSP90 beta)
Class: Monoclonal
Reactivity: Human ; mouse ; bovine
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Moravian Biotechnology
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-HSP90 beta [MBH90B]
- Clone: MBH90B
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: Calculated: 83264Da (Hsp90?); SDS-PAGE mobility (reduced): 90kDa
- Reactivity: Human ; mouse ; bovine
- Host: Mouse
- Disease: Non-small cell lung cancer
- Description: Antibody created to detect Hsp90b protein. Binding specificity: protein Hsp90b, calculated epitope EEVHHG.
- Immunogen: EEVHHGEEEVEC sequence of beta forms of heat shock protein 90
- Isotype: IgG1
- Production details: B cell donor: Splenocytes from mouse immunised with peptide EEVHHGEEEVEC, fusion partner: SP2
Target Details
- Target: beta forms of heat shock protein 90 (HSP90 beta)
- Molecular weight: Calculated: 83264Da (Hsp90?); SDS-PAGE mobility (reduced): 90kDa
- Target background: Hsp90 is involved in maintaining the conformation, stability, activity and localization of several client proteins that trigger key points of oncogenic transformation (like mutant p53, steroid hormone receptors, HER2/neu, C-RAF, CDK4/Cyclin D, telomerase hTERT, etc.). Therefore, modulation of this single target offers the prospect of simultaneous inhibition of multiple signaling pathways and biological processes that might be implicated in the development of the malignant phenotype.
- Epitope sequence: EEVHHGEEEVEC
Handling
- Format: Liquid
