Cat. #151384
Anti-HRX [HRX107]
Cat. #: 151384
Sub-type: Primary antibody
Unit size: 100 ug
Target: Histone-lysine N-methyltransferase (HRX, MLL, ALL1, Htrx)
Class: Monoclonal
Application: ChIP ; IHC ; IF ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jacqueline Cordell
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-HRX [HRX107]
- Research fields: Cancer;Genetics
- Clone: HRX107
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ChIP ; IHC ; IF ; WB
- Description: The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Lukaemia through translocations that that result in its fusion with a variety of heterologous partners
- Immunogen: Synthetic peptides corresponding to 839-854 of the HRX protein
- Isotype: IgM
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Histone-lysine N-methyltransferase (HRX, MLL, ALL1, Htrx)
- Target background: The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Lukaemia through translocations that that result in its fusion with a variety of heterologous partners
Applications
- Application: ChIP ; IHC ; IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Mueller et al. 2009. PLoS Biol. 7(11):e1000249. PMID: 19956800.
- Misguided transcriptional elongation causes mixed lineage leukemia.
- Butler et al. 1997. Blood. 89(9):3361-70. PMID: 9129043.
- The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures.
