Anti-HPV16E2 [TVG 271]

TVG 271 is useful for detection of protein in cervical lesions. TVG 271 completely inhibits E2 binding to E1.

Contributors

Inventor Institute
Lionel Crawford University of Cambridge
Cat. #: 151168
Tool sub type: Primary antibody
Unit size: 100 ug
Cancer types: Gynaecologic cancer
Research Fields: Cancer;Microbiology
Application: ELISA ; WB ; ELISA ; WB
Target: Human Papilloma virus-16 early protein 2 (HPV16 E2)
Reactivity: Human papilloma virus
Clone: TVG 271
Host: Mouse
Class: Monoclonal
Product description: TVG 271 is useful for detection of protein in cervical lesions. TVG 271 completely inhibits E2 binding to E1.
Conjugation: Unconjugated
Isotype: IgG1
Immunogen: Maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE)
Myeloma used: P3/NS1/1-Ag4.1
Target background: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: '-15° C to -25° C
Shipping conditions: Dry ice
References:

Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.

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