#151198

Anti-HIF1A [Ha111a]

Cat. #151198

Anti-HIF1A [Ha111a]

Cat. #: 151198

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Hypoxia-inducible factor 1, alpha subunit (HIF1A)

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Helen Turley

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-HIF1A [Ha111a]
  • Research fields: Cancer;Genetics
  • Clone: Ha111a
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours. HIF1A has been observed in varying subsets of tumour cells from various solid tumours.
  • Immunogen: GST-human HIF1A amino acids 329-530 fusion protein
  • Isotype: IgG2a
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Hypoxia-inducible factor 1, alpha subunit (HIF1A)
  • Target background: Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours. HIF1A has been observed in varying subsets of tumour cells from various solid tumours.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Andr et al. 2008. J Biol Chem. 283(43):29375-84. PMID: 18694926.
  • Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
  • Wiesener et al. 1998. Blood. 92(7):2260-8. PMID: 9746763.
  • Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.