#157718

Anti-GTP [2A4]

Cat. #157718

Anti-GTP [2A4]

Cat. #: 157718

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: GTP

Class: Recombinant

Application: ELISA ; FACS ; IF

Reactivity: Human

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Urpo Lamminmäki

Institute: University of Turku

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-GTP [2A4]
  • Research fields: Cancer;Metabolism
  • Tool sub type: Primary antibody
  • Class: Recombinant
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Application: ELISA ; FACS ; IF
  • Description: GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner. Ras GTPases are frequently mutated in cancer and so far only few experimental inhibitors exist. The most common methods for monitoring GTP hydrolysis rely on luminescent GDP- or GTP-analogs. (From Kopra et al Anal. Chem. 2015)

Target Details

  • Target: GTP
  • Target background: GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner. Ras GTPases are frequently mutated in cancer and so far only few experimental inhibitors exist. The most common methods for monitoring GTP hydrolysis rely on luminescent GDP- or GTP-analogs. (From Kopra et al Anal. Chem. 2015, 87, 6, 35273534)

Applications

  • Application: ELISA ; FACS ; IF

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-GTP [3A5] recombinant antibody

References

  • Kopra et al. 2017. Anal Chem. 89(8):4508-4516. PMID: 28318223.
  • Kopra et al. 2015. Anal Chem. 87(6):3527-34. PMID: 25707436.